In December my wife and I funded a couple of microfinance loans through Kiva.com to a group of women in Uganda who needed to buy another sewing machine and some cloth stocks to build up their business. The loan was fully funded in January 2008. Today Kiva reported to me that they have already repaid 25% of the loan.
We always talk about bottom-up solutions on this blog. Kiva.com is the real deal and I hope you support them.